As far as I know, physically it is quite strong, its tiny size helps a lot in this regard, so to achieve substantial physical damage, you also need to ruin the bag: burn it, cut it up, etc... you could also deactivate them digitally, but the Vuitton chips are password protected.Curious about this chip… how fragile is it? What would damage or deactivate it?
One thing that is rarely mentioned, is that these chips have a best before date. People freaked out about not having the printed codes anymore, but almost nobody though about the only really serious problem with the chip: that while a date code from the early-90's is still visible and readable, the chip won't work in a few decades. Vuitton picked one of the best and most expensive RFID chips, but even that has an "up to 10 years" lifespan. So to sum it up, these chips are quite strong, the real threat for them is time itself.