I purchased my Barenia B35 (PHW) in 2017 and it was $13,100 plus tax, so almost $14,400, and the price has gone up I believe twice since then. You'll be well over $15K at retail.
So the question is really...are you open to resale? At resale the price will be a LOT less especially for a 35, but the bag won't be perfect.
Now as a Barenia owner I'm going to tell you that your bag won't be perfect more than a few minutes anyway

It will get marks.
So that's your call.
Barenia being push offer only, it's HARD to find this bag. Even so, personally I think $22K is pushing it. I would negotiate. I would also do a search in the forum on this particular reseller, who has been quite vocal and active here and has made some strong statements. But, again, it's how much you want a brand new bag, and whether you are willing to wait.
Also keep in mind that there are Barenia superfakes out there, using real Barenia. So at this price at resale you need to have a guarantee that if H spa finds your bag inauthentic one day, you have recourse.
This is a wonderful bag and one of my absolute favorites, so good luck!