I love the Damier! (I have the 30) The mono is nice, but both are classic patterns on a iconic bag! You can't go wrong.
*What I have noticed, is that there are often variations on the Mono: Mirage, Perforated, Graffiti, etc...you might decide, like I did, that you prefer your mono to have a little something 'extra'!
I also thought you meant multicolore from the title. I like damier best and it was actually the first LV pattern (learned that from aprior purse).Love the lack of vachetta. It is my rainy day purse.