I don't think the Neverful is durable enough for it's intended use as a tote bag, at least not for my work but I do use it for golf with lightweight things in it but I can't really put a laptop or tile samples in it and carry it around like I can other work totes like my Chloe Woody. However, my Speedy graffiti rose is one of my go to bags for situations where I know I am going to be sitting a table that is sticky and people will be brushing up against my bag (i.e. Top Golf, a brewery, or my son's sporting events). I have had my Speedy since 2009 and it looks brand new but I only use it 10 times a year or so. I feel too stressed out to take my Chanel bags anywhere like that, especially my tweed and when I do take my tweed bag out, I literally bring the dust bag to put it in when we are eating if my son is with us. Also, when I am driving in my car with my Chanel bags, I put them in their dust bag and buckle the seat belt around them and I don't do any of that with my LV bags. In fact, the only other bag I do that with is a white shearling Chloe bag. I worry so much about my Chanel lambskin bag and metallic leather getting scratched. They just seem so much more fragile than LV, but that isn't necessarily that they are not quality but perhaps more fragile materials.
I guess after that long ramble I could sum it up as both are great quality, IMO but LV seems more utilitarian and Chanel more for looking pretty.
On a different note, the Chanel SAs are a million times nicer and less racist.