I am very careful the first few weeks I carry my bag but afterwards, not so much. I am not reckless with my bags though - I don't carry them in the pouring rain but when it's lightly drizzling I wouldn't think twice about bringing my epsom Birkin with me. I am not afraid of placing my bag on the ground but cover my bag with my jacket or shrug if I'm at a restaurant with sizzling plates. I remove the stickers right after purchase, keeping them on is one of my pet peeves. I also make sure I put anything that could spill or is sticky in a pouch or ziplock bag before I dump them inside. I use twillies because I'm a mild germophobe, I like the option of washing the twillies every once in a while to keep handles hygienic. I don't use any interior protectors or bag organizers but I'm guilty of overstuffing my bags every now and again.