Depends how badly I want the bag and how noticeable the stain is. I'm slightly OCD so I would have to REALLY want the bag to get it with an imperfection
Only if it was in the original price $1000 and up dept. Then I would definately consider it depending on what and where the imperfection was on the bag.
You can find them at some designer outlets, Nordstrom Rack, TJ Maxx, Off Saks 5th Avenue, or in the sales section of most dept stores. Last time I saw a green Mulberry bag with slight imperfections under 50% off on the Nordtrom's sales table.