Ooh, this is a good thread but I have to break the rules. I absolutely cannot stop at 5.
DRAMA
#1) West Wing - hands down
#2) The Shield
#3) Homeland
#4) Damages
#5) Dexter
#6) The Wire
#7) Breaking Bad
#8) Mad Men
#9) Sopranos
#10) Game of Thrones
#11) Sons of Anarchy
#12) Borgias
COMEDY/ OTHER:
#1) Will & Grace
#2) Sex & City
#3) Girls
#4) Seinfield
#5) House of Lies
#6) Veep
#7) Californication
#8) Shameless
#9) Nurse Jackie
#10) Curb your Enthusiasm