Neverfull GM (Mono, mostly because the straps are more comfortable than a DE, but if you don't like Mono then maybe DA splits the difference for you?) for work (with a 15" MacBook Pro!) or as a travel bag. Alternating it with the Totally MM (DE) and a YSL Sac de Jour. If you don't mind a more "masculine"-colored bag, I also sometimes put my computer and papers in my Renzo Messenger Bag (Damier Graphite) and then carry a smaller purse. I think it's understated, chic and durable.