There are quite a few options, even if they may not have a specific compartment for a laptop. But many seem to require some kind of compromise in terms of practicality.
The Victoria light briefcase can fit 1 - 2 laptops and has an easy to use zipper closure. It doesn't come with a shoulder strap option and no outside pocket. The latter may be less of a nuisance because of the zipper closure. It's 40 centimeters, so it should probably fit a 15inch, not sure about the 16.
The sacs a depeches and all the kelly briefcases have the troublesome flap closure, no outside pocket and no shoulder strap option. Kelly depeches 37/38 won't fit your laptops. I would love to get more use out of these bags with a flap closure, but in reality I hardly end up using them. This is a personal preference of course.
The recent herbag messenger 39 has the troublesome closure, but it has both an outside pocket, shoulder strap option and can probably fit a couple of laptops with no problem. Not big enough for bigger laptops though (15 -16 inch).
You could also probably use the grooming bag as a laptop bag, it certainly is big enough, but it is much more casual than the other bags I mentioned. It has a shoulder strap option and is really practical.
A birkin 35 and bigger should be able to carry a 13 inch, a 40 or 45 could carry bigger ones laptop with no problem. I wouldn't worry about the handles, they are really solid rolled handles. If you are carrying the bag every day, the wear and tear should be more of a worry than stretching them. The handles can be replaced in a worst case scenario and you will likely need to send them to the spa for reglazing if you carry the bag a lot after a while anyways. Birkin obviously has no shoulder strap option, but it is a really practical tote.
There quite a few other options when it comes to seasonal bags that you could also consider.