Well it sorta depends on if you want a neutral palette or a colorful one. Do you wear a lot of colors for clothing or do you wear mostly neutral? If you are like some of my friends that wear mostly denim, black, white, tan and khaki then I would get the holiday patchwork to throw in some color into the mix without having to buy new clothes to match it. If you wear a lot of colored shirts and such then the neutral fall patchwork will set it off nicely and you won't have to worry about what color bag you match to your shirts each day, etc.
I personally think the prettier scheme of the two is holiday patchwork but that is because I love rich velvety colors like the blues and the burgundy set off by gold....
I do adore animal print, however. Each bag is unique and can serve a different purpose!