I think you should use whatever you think you will like best. I have many LV bags, but I personally never felt the need to use an LV bag for my diaper bag. I used a Kate Spade and a Petunia Pickle Bottom. They were convenient because they came with the pockets and organization that worked well for a diaper bag. And if milk spilled in them I did not care at all. When going out and needing a full diaper bag, I would carry a small purse or pochette. Other times I would throw a couple diapers, bottle and wipes into my big purse and leave the diaper bag home. I have a DE NF GM and if using it as a diaper bag, your idea to use a purse organizer is a good one, because it will become a black hole otherwise. Congratulations to you! And I hope you find the perfect diaper bag for you!