I'm sure you could find a lovely clutch, crossbody or wristlet from any of the major designers which you could use to hold your Kindle. Depending on how much you'd like to spend, you could choose from Hermes clutches & pouches to
Coach swingpacks & wristlets.
At the current time, Cole Haan and M-Edge are the big players in the Kindle covers, but there is a wide variety in designs and materials. You should also look Kindle sleeves, some of which look like pouches.
As for other designers that you mentioned making Kindle covers, they would be wise to wait until the e-book business sorts itself out in regards to platform. Currently, there are several e-Readers available, including Sony, Kindle and Nook, which were recently joined by Apple's i-pad.
I bought the M-Edge with hinges in black leather, so when I read on the subway, it looks like just another leather-bound agenda. OTOH, my youngest niece has a bright lime green neoprene cover, and a writer friend has what I thought was a mock croc wristlet/purse but is, in reality, a Kindle jacket in amethyst! While riding the subway recently, I saw what looked like an old New Yorker magazine cover hiding a Kindle. Interesting choices, all.