Well it's not the clearest picture and I'd never seen it before, but I'm sure it wouldn't look odd. I find that most of LV's men's bags are really quite unisex.
In any case, I think it's much harder for a man to pull off a woman's bag (though many do manage it very well) than vice versa. If you love it, I say go for it!!
Does anyone know the price and name of the bag, btw?