I think you may need to look at the list(s) of ingredients on each product, as depending on brand and country 'conditioner's' and 'creme's' meaning can be interchangeable.
There are 2 or 3 stages to conditioning: cleaning, feeding and protecting. It's at the cleaning and protecting stages one has to be most careful.
Cleaning: Some cleansers (including saddle soaps on some leathers) can strip leather of its natural moisture, can take off the finish and open pores making it more susceptible to the damage from the elements. Be very careful if anything calls for more than the merest drop of water.
Protecting: Wax in a product will seal leather, repel water and restore shine but it can also mean that no further moisture can be added if/when needed. Similarly silicones and other ingredients in products can make leather look better but only short-term*.
Feeding is where (usually) leather cream comes in. It puts back natural leather-compatible oils into the leather and makes it less liable to crack, softens and protects longterm.
*Shine should come from continuous brushing (polishing) between wearings, leather's natural sealant.