No the screw won't come out completely, unlike the original design, the screw for the new closure is integrated to 1 half of the bracelet. But once the screw is loosen too much then half of the bracelet just get detached altogether, that's how some lost the bracelet. No one lose the screw alone in the new closing mechanism anymore.yes, but i would rather lose a screw than the bracelet. I don't wanna take any chances. Now I'm always checking the screw that keeps getting loose. Someone above said the screws can still fall out with the new mechanism. I read someone saying to put glue on it but I do not know if that will be a good idea.
Of course no one wants to take any chances to lose the bracelet. You may want to go to Cartier and raised your concerns since some posters had gone to Cartier to have the problem rectified.