When my oldest cat Charlie was about 2 yrs. old, we adopted a 3 mo. old male from the humane society. Even though both were males, Charlie became a surrogate "mother" to Oscar, just like your two. They were incredibly bonded. Charlie was always a very friendly, loving and nurturing cat. When Oscar was about 6 mo. old we moved. Oscar had no problem adjusting, but Charlie... well, he spent nearly a week under our bed! He wouldn't come out for anything. This was totally out of character for him. I finally had to put some food, water & a small litter box under there with him. Although Charlie wasn't as vocal as your cat seems to be, he was definitely very stressed by the change in his environment. Maybe the older they are, the less readily they adapt to change. I agree with everyone else though... give him lots of love, attention and reassurance. Once he begins to feel secure in his new surroundings, he should settle right down. Cats can be even more needy than children sometimes, but just like kids, their love is worth the effort.
As a side note, I have another cat, a 16 yr. old spayed female who has always been fairly quiet... until the last few months. She started "crying" in the middle of the night too, for what seems like no apparent reason. Sometimes all it takes is for me to call her name & she stops (that reassurance thing perhaps), but other times she keeps going until I get up and check on her. I'll often find her in the hallway with one of her toy mice, or something like that, laying at her feet. Obviously she's trying to tell me something, but since I don't speak "Cat", I have yet to figure it out.
Be sure to post an update in about a week to let us know how Panko is doing.
As a side note, I have another cat, a 16 yr. old spayed female who has always been fairly quiet... until the last few months. She started "crying" in the middle of the night too, for what seems like no apparent reason. Sometimes all it takes is for me to call her name & she stops (that reassurance thing perhaps), but other times she keeps going until I get up and check on her. I'll often find her in the hallway with one of her toy mice, or something like that, laying at her feet. Obviously she's trying to tell me something, but since I don't speak "Cat", I have yet to figure it out.
Be sure to post an update in about a week to let us know how Panko is doing.