Very Interesting question. I have no idea but would love to know as well. I just got my first Gucci and have not done a thing to it. However, on my denim LV I did spray a water repelent. I am not sure if it would work for the Gucci bag.
I spoke to SA at gucci and she said fabric is pretreated. She said you can spray scotch gaurd on it and no problems. Also, if you need to clean it, she rec going to repu dry cleaner you trust.