I LOVE muse for school as a work bag (oversize I have). It can carry a ton. I am not bothered by stitching, because the bag does not lose in elegance, you can always use tiny bit of transparent nail polish to mend it.
I use two more bags for school as well (I maybe even carry more than a student because I am an instructor, and tote all the papers and books school-home) . I use Muse II large size when I want to look super classy (conference, so I carry lap top and tons of papers. The third one for largest workload, ALL possible books and papers -- medium Downtown.
I would definitelly suggest downtown as the most effective, covering all options and still looking AMAZING, but OS Muse will do great.