The Food Bank, the local Human Society, other animal protection groups (I prefer local ones, so the London Animal Alliance gets $$$ !), also the Red Cross.
I really prefer smaller groups over larger ones, so for instance, there's always fundraisers on campus for small targets, e.g. sending children to school in so and so (a student had done her ethnography time there and wanted to give back to the community, a group sponsorred a small community in Sierra Leone and wanted to send the children to school), local food drives and the such.