What bag feels best to carry?

I love any bag that goes on the shoulder... it makes it all much easier. My PAddington is awesome for that-- not too heavy and hangs just right.
i like hobos best. i've found that shoulder bags with two straps often fall off my shoulder and i don't like messengers. chanel has the softest leather i've ever felt.
I tend to switch off between a shoulder bag and a hand-held. It keeps me from getting shoulder and neck pain. For a hand-held bag, it has to be able to fit over my arm, so I can still have both hands free. I also prefer a single strap on shoulder bags, but it really depends on the bag.