I have lots of stomach issues and I have been on Dexilant (60 miligrams) for years. Its recently been on the news that long term use can cause kidney failure. I called my gastroenterologist and asked to be taken off the Dexilant but was told I have too many stomach issues and I needed to stay on it. I was told only a small percentage had the kidney failure side effect. I didn't find that comforting so I went to a doctor who helps people wean off or cut back on the medication. First I was put on an elimination diet, then 2 weeks into the diet I went from 60 milligrams to 30. The first 2 weeks of the diet my stomach was upset and I had a lot of bloating and pains. Then I kind of settled into the diet but I had a lot of exhaustion and flu like symptoms. I was told it was like withdrawal and to take it easy. No strenuous exercise, so I stuck to yoga and walking. I'm better now and my primary care dr is happy I am doing this. He highly recommends the doctor I'm seeing. 2 weeks ago I went from the 30 milligrams of Dexilant to 20 milligrams of Prilosec and I'm suppose to add food back in to see what my triggers are. Soy is one. We found that out early on. My problem is my stomach bothers me every time I try to add something. I started with cheese (I'm suppose to add a new food every 3 days). First two days were ok, but third day had issues. Tomorrow I'm suppose to start taking the Prilosec every other day but I don't think I can cut back any more. My stomach hurts and feels uncomfortable. I eat Gin Gins which is a ginger candy which helps but I don't know if I'm going to be able to get off this medication. I feel like I'm having acid reflux again. I have had anxiety since I was a child and my anxiety aggravates my stomach. Ativan helps but I don't want to take it all the time. Has anyone tried to wean off the PPI's? Or deal with stomach issues and anxiety? I also have IBS but I'm on a great probiotic VSL#3.