I think it is more of a design preference as far as which is preferred.
What is this about the handles peeling? This has popped up in a few threads and I don't know specifically what it means.
my speedy damier handles peeled and then when i got the speedy back from repair, there were stains there i know where not mine and it looked like it had been heaviely used while it was away from me. sadly i didnt take enough pictures before sending it in to prove my case, but i would in future take TONS AND TONS of pics of my item before sending it in for repair.
Personally the mono is the classic LV. I love the mono speedy. The handles can get dirty but I have had mine for 3 years and they still look lovely.
The damier speedy is one of my favorite bags, it is worry free! I love the damier print. It is LV without the more obvious logos. I love the red interior. I don't think you can choose one is better than the other.....simply decide which one to buy FIRST!!!! Then buy the other!!!!!