The cream would definitely be easier to wear and match with a wardrobe but I personally love the pop of color with the orange bag. Depends on your style and how you think you would wear it.
I love the orange, honestly. I think it's fun and can actually be worn year round. I would worry that the cream would get color transfer and get dirty easily. Have fun with some color!
I like both colors very much! The cream will be more timeless, while the orange is more special and it's a nice pop of color. I tend to the orange, if you have some neutral colors on your other bags!