Yeah, I have been using my light blue vernis thompson street nonstop since I got it six weeks ago. I have had no problem with color transfer and I live in humid florida! I also took it to vegas last week and it held up in the rain. I had it under my coat, so the vachetta wouldn't get wet, but the vernis got a bit wet and was still fine.
The bag is about 6 years old too (bought used off ebay) and it is still in almost perfect condition. I don't know how much the person I bought it from used it, but I have had no problems with color transfer or anything. I even keep it in my desk at work without its dustbag.
The bedford is next on my list of things to buy, so I say go for it! The framboise color is darker too, I don't think you'd have that big a problem about color transfer. I think as long as you're aware and don't set your bag down on something like wet newspaper, it'll be a great everyday bag.