I have both (PM size) and my favorite is the Galliera. Even though it doesn't zip closed, it stays securely closed. Also for wearing on the shoulder, I think it's less awkward than the Palermo because it's not as boxy and the canvas on Miss G is softer. If you mostly carry your bags in your hand, though, pick the Palermo. A Palermo is easier to get in and out of, though.