I use my Burberry Nova Check Tote. It holds everything. I use it as a diaper bag sometimes. I love the size because it holds my water bottle and makeup. Love it!
i use my coach patchwork when i go to work, but when i go shopping i use one of my LV's, i love my Galliera PM but i use my Hampstead PM ebony when it's raining......
The bag I've used the most is my Marc Jacobs Teal Stam. I have a black stam (pleated), but haven't used it as much because the leather lining scares me...I'm so scared to scratch it! Also, on my teal stam, the leather isn't as delicate (or atleast I'm not so worried about it). The handles fit over my shoulder, and I also have the option of the chain strap. For a more casual look I can even take the chain off. It's also quite big without looking like it, when I was sick I was able to carry a tissue box around with me
ETA: and the color is more neutral than I thought! It goes with almost anything in my wardrobe.
My lt. brown Hogan Guitar bag and a Banana Republic dk. brown leather tote (with lots of pockets) get the most use. I have a feeling that my new Jenny Yuen plum Hitchcock will get pulled out very often come next fall and winter.