i know quite a few people (including myself) who ONLY take online classes.

right now, for hubby and i going to an in person class just does not work with our full time jobs. we will have to commute eventually (he starting in may and me starting next year) because our fields of study include lots of hands on labs and internships (EMT and radiology tech), but a girl i work with will be able to get almost her entire BS in accounting online. my good friend is about seven months pregnant, and online classes are safer and easier for her until the baby comes. that said, when i went to college the first time around (at a LARGE state university) i had lots of friends who HATED their online classes. most of them were very social. there not enough interaction with other classmates for them to learn and it was hard for them to organize their thoughts in written form for EVERY class related discussion/assignment/lecture.
i personally prefer online classes, especially for pre reqs that everyone has to take (ie intro to writing, western civ, art history, etc)...you know that annoying person in class that always runs off at the mouth, asks the questions the professor has already answered, and says stuff without thinking? online, if you don't like what someone is saying, you can just stop reading! plus, i collect my thoughts better on paper...i feel like i am communicating more effeciently when i can write things down.
it really depends on if you prefer learning through social interaction and lecture or through reading and independant study. you will know your learning style best.