My new Pochette Métis smelt like a plastic/chemical smell. It did get fainter and fainter though. I can still kind of smell it in the interior slightly. A couple of others have complained about the PM smelling the same.
Makes sense that if they changed the chemical to make the canvas less crackable it might smell different. I haven't been in LV for a while and the items I do have didn't smell even when they were new. But I have had other brands of coated canvas (that had a softer feel than LV's) items that smelled. Particularly a Kathy van Zeeland that gave me a headache every time I opened the drawer it was in! And a Guess wallet that smelled like fish (but it was leather, I think it was some oil used in curing the leather).