The miroir is made of vinyl aka plastic and the interior lining is cotton and polyester. If you look on vuitton.com and look under silver, you will see the speedy and papillon and it tells you the materials. HTH
I wore my speedy out for an evening my sa was walking past me and grated his watch across it, no marks. I swear to god I freaked! LOL I also tried to scratch mine and nothing. After the whole night out I checked it in the daylight the next day and no so much as a scratch. So in my opinion its definately NOT a fragile bag. I was more concerned about if it would crease from having stuff in it..but so far it didnt.
I actually replaced the cardboard with those air pockets for shipping. Easier in and out and holds the shape well. the cardboard is kind of hard getting in and out and I didnt like how much I had to torque the zipper to pull it out.