Funny you bring this up... I have only mainly taken LV or other designer bags to a job interview... so I don't see taking a Speedy will be any harm... At my last interview, I took my Mahina and had no problems!
I just say no because you never know if someone is a secret brand snob- Maybe one would think, well you couldn't need the job too much if you are carrying a 700 dollar purse, now, I dont think like that, but there are weird people who take such things like that into account- But I am only talking monogram because its the most obvious- I think if someone should bring an LV to a job interview, it should be understated, like Epi or Damier, just my opinion though!