Dooney & Bourke had a whole line of leopard/leather bags in various styles. Don't think they have any on their web site at present but you can find a whole bunch on ebay by searching for "leopard Dooney." Dooney's leather tends to be very nice and they don't cost a grand.
Mulberry has also done their classic Bayswater in a number of different leopard styles and colors. Here, at the very high end, is one:
http://www.mulberry.com/#/storefront/c5586/4329/category/
You can find modeling photos of the other leopard Bays in the Mulberry forum. They did a brown leopard, a blue, a silvery, and a fuschia. The brown is very pretty and there are lots of modeling photos of that. I think they retailed for about $1K.
Love the leopard prints!