Hi all: A couple of weeks ago I got a AWL D&B bag from fleabay that 'comes from a smoke-free home'. lol. It reeked reeked reeked of cigarette smoke. I was pissed but rather than get in a neg war over a $35 bag I decided to look in this forum and use it as practice. I saw a lot of suggestions for wiping, for airing, and for baking soda. I wiped the inside of the bag as best I could using paper towels dampened with water and dish washing soap. Didn't do much for the smell, but what a lot of gunk came off! When my AC fan coil unit was on, I opened the purse up and laid it on top. When it wasn't, I left the bag in front of an open window. A week or two of this, there was some improvement, but still a long way to go. I kept scratching my head over the baking soda thing. If you know those vintage Dooney's they are not lined, and have lots of crannies, and I was afraid I would never get it out. Ditto with cat litter. I kept trying to think of another substance that I could experiment with. It hit me to try rice. Rice is hygroscopic so I thought maybe it could absorb odors as well. I filled the bag up 1/8th of the way and closed it. A couple of times a day, I shook it up to distribute the rice. I did this for about a week. Yesterday I emptied the bag. I'm very pleased. The odor is not completely gone yet, but I'd say an 80% improvement. So rice is something to consider. I'm going to give another wipe-down and do a rice repeat and see how much further I can get.