I agree with all of you above. Newspaper print is a nono. I still say washing your hands and keeping your hands clean is 99% of the battle. Some people don't wash their hands as much as others, or use more hand cream than others, etc. It also depends on where you work, what you do, some hands get dirtier than others obviously. I spay with Apple Guard as soon as I get the bag. I do it once a month at least. I also bought the handle care and use it after the Apple Guard. Too early to really know if the Handle protector works, but so far it looks good. My whites are as white as when I took them out of the box. I am going to take pics of my newest white City. I will take pics in a few months to compare any changes.
I do think that if you carry your bag by the handles most of the time, instead of using the shoulder strap or carrying it in the crook of your arm, they are going to get dirtier faster.
We see bags that are 3 years old with perfect handles and bags that are 6 months old with filthy black handles. There must be some reason. *wink*