Hi Sez, I know this post is really old, but I’m wondering if you ever had any luck figuring this out. My family has the same problem. We put on a clean shirt and sometimes within minutes of being outside, the shirt smells like a wet dog. I know for a fact that for us, this has nothing to do with how we do laundry. We have already purchased brand new shirts and worn them before washing, and they do the same when we go outside! We consider maybe it’s something in our sweat reacting to the material, but why does it happen to everyone in my household? My husband doesn’t have the same genes as me. Perhaps it is some type of parasite or something contagious within our household and that’s why it happens to all of us. I know it may sound silly to some people, but this doesn’t happen to everyone. That much I know. I can understand if it was just me and my girls having the problem because we have the same genes, but why does my husband suffer with this problem too? Also, we didn’t always make clothing smell like this. It’s only come about in the last 15 years or so. Not all shirts do it, or at least if they do, it isn’t near as bad. It seems anything synthetic. God forbid we wear one of those “quick dry” sport type shirts made by Nike or Under Armour. Today I washed my daughter’s volleyball jersey, and hung it outside to dry and it threw me off because it smelled good like detergent when I hung it out. When my daughter brought it in, it smelled like wet dog before she even put it on. So now I’m considering maybe it isn’t our body’s reaction to it. I don’t know. Then I considered maybe even though I washed it, the proteins from her sweat were still in the shirt, and that’s why it smelled after being hung outside. I’m at a loss, and wouldn’t wish the smell on anyone. Last year my daughter wore a costume for Halloween, and when she came in the house, the entire room instantly smelled like wet dog. It was so bad. I’m hoping you see this reply, and respond. I’m curious if you ever resolved the problem.