NYCFashionista, I think you'll be fine as the Vitello Elite on both front and back of the bag you'll be able to wipe off any wet surfaces right off. The leather is very similiar to Prada's saffiano. The sides you can just wipe off and there shouldn't be any kind of spotting especially if you decide to get a darker color.
Just sharing my own experience though I have only had the bag for 2 weeks - I think it will be fine as long as it's not a storm! The leather feels quite sturdy. I have accidentally spilled tomato sauce on the bag the other day and it came off with a simple wipe and no stain!