Yes, religiously!
Cleaning ritual depends on type of shoes:
Boots (mid to high)-- Interior, light wipe when needed. Exterior, cleaner/protector when needed.
Booties (open toe, strappy, ankle)-- Interior, after every wear. Exterior, light wipe when needed; cleaner/protector when needed.
Heels/Pumps-- Interior, after every wear. Exterior, light wipe when needed; cleaner/protector once a year.
Flats (ballet, open sandals)-- Interior, after every wear. Exterior, light wipe when needed; cleaner/protector a couple times a year.
Flip-flops-- Light wipe when needed.
Storage depends on frequency of wear:
Daily-- Designated rack/shelving
Weekly/Monthly-- Stackable storage boxes w/ easy front-open access
Once in a blue moon-- Original tissue/shoe tree in each shoe and back in original retail box
When possible upright storage is most beneficial in preservation of shape and prevents unnecessary exterior markings (especially for suedes).