It really depends on a few factors.
1) How often will you use it?
If you're the type of person who rotates wallets, chances are it will remain relatively clean. If you're going to use the same wallet for years, it will eventually get a little dirty and gray over time.
2) Leather type and texture.
Leathers with more texture such as grained or pebbled leathers or epi leather are more scratch resistant, but they are also more likely to build up dirt and grime overtime. Much easier to see that build up on light-colored SLGs.
Smooth or box leathers are easier to clean but also are easier to show wear and tear (light scratches can be buffed out) and can stain and show staining more easily.
A quick glance at pre-loved sites can give you an idea of what a beige/nude or light color wallets will look overtime.
https://www.fashionphile.com/shop/accessories/wallets?categories=beige&sort=date-desc
If you zoom into close up photos you may be able to find the dirt buildup that has accumulated overtime. And that just life.
YSL's grain de poudre nude or beige leathers are known for accumulating build-up overtime. I remember seeing quite a few dirty ones on the pre-loved market a while back.
Here is an unfortunate example:
View attachment 5684729
3) What products do you use on your hands?
Hand sanitizers and lotions, while great for keeping clean and moisturizing the skin, can leave residue on items overtime, especially if not properly dried or completely absorbed into the skin, respectively.
I am not a fan of hand sanitizers for this purpose. I keep one on me for emergencies but I much prefer to find a restroom to wash and dry my hands.
4) What other items will you carry in your bag on a daily basis?
Other items will touch and bump against SLGs in a bag, we all know that. Some may cause color transfer, so that is something to be aware of. For the most part, honestly, it should be okay. But everyone carries different things in their bags, so it's more of a thought than anything.
I'm not trying to scare you. I am pretty cautious about buying light colored bags and SLGs because I am very heavy handed with my items and do not baby them. I have a YSL darker beige cardholder that I've been using for the past 6 months that has been wonderful, but I made sure to buy a darker beige color knowing my lifestyle and habits.
If you're the type of person who takes care of things, chances are you're probably much better than me and it will be okay.
Hope that helps, good luck!