anything overly studded is done, any bags that were overly "inspired" by the "downtown" style designers such as Chloe, or Mulberry - they are the leaders and all the trickle down gets boring...and when you see it at $25 per bag, you stop and think...you bought one generation of "inspired" bags from an indie designer, and then there are more "spawns" of your bag trickling down even further, to the low mass marketplace...
I love indie designers though, as often they are the ones that create the buzz (only when they do somethng really new and fresh)...they have a lot of guts to put out things that the big guys probably wouldn't do, as they have target customers and a name to uphold.