I have the NF GM and a pair of Delightful MMs, both are great bags but I personally find the Delightful more comfortable to wear and more practical as an actual purse. The MM has a more noticeable slouch, so it doesn't sit as high up as the PM, and is a bit easier to gain access to while on the shoulder. With that being said it only has a single strap and can slip off more easily if you have sloped/rounded shoulders and it's one giant cavern inside.
The NF is an open-top tote which is great for travel, a book bag, or if you just generally carry a lot of things but it does have a short handle drop so it will sit high up. The straps are also thinner and have a tendency to dig in when the NF gets heavier which is easier to do because of the size. It has two straps and is less likely to slip off as easy as the Delightful but again is just one giant cavern.
I don't have the Totally but it has a zippered top for added security and has both interior and exterior pockets to help keep things accessible and organized. It has two wider straps and the handle drop is more generous than the NF MM or Delightful PM, as for comfort I can only assume it would be second to the Delightful given that I have a bag with identical straps. Like the NF it's more likely to stay on your shoulders because of the double strap design, is easier to access despite the zipper, but some people say it looks a lot like a diaper bag...I personally think it looks practical and functional.
As to which one you choose, if any, is completely dependent on your personal taste and lifestyle. Good luck deciding
