I know it's rare but here's my story: I went to an excellent, highly reputable cosmetic dermatologist to get my first botox injection. I had the shot at 10:30 A.M - At about 5 A.M the next morning I started getting horrible stomach cramps which turned into full blown food poisoning. For 36 hours I was feeling like death - It didn't register right away because it is almost impossible to find cases like this - so I blamed it on some shrimp I had eaten at dinner but the coincidence is a little too weird - I think it was the botox. Please read all the precautions before you ever decide to go this route, every single person is different - and I guess I'm one of them. No more botox for me!!!!!!!!!