YES! Mine is the MM and even if not fully loaded, it kills my shoulder---not right away, but over the course of the day. It is the only bag I regret.
It is lovely, don't get me wrong, but not practical for me.
Maybe I have extra boney shoulders or something...
Yikes! Okay, I guess that's a bag I'll never own...I have boney shoulders...it's a cute bag, though!