I guess I'm gonna be the first to be the odd one out. If you were checking it in and knew it would be banged around a lot then I would not recommend getting it.
But if you're getting the azur keepall to be carried-on and always carried by yourself - then I would think the main risk is getting the bottom of the keepall dirty, however, the rest of it should stay ok. Probably the biggest concern would just be watermarks on the vachetta. But the coated canvas like all the others are pretty durable and I'm sure any marks on the coated canvas part can be easily cleaned.
Looking at the threads of the azur being photoshopped with patinaed vachetta, it looks really good.
So if you have a high preference for the damier azur over regular damier - I'd say just get it! However, if you don't have a preference either way - then I guess it would almost make sense to go with the regular because it's definitely more low maintenance.
Good luck with your choice!