You're welcome! In terms of the weight of the bag, I think the LockMe might be lighter since it's so soft, but the epi leather is not too heavy either. For a daily-wear bag, I would go with the Grenelle over the LockMe since the epi leather feels sturdier to me, and that is an important consideration for a bag I will use on a regular basis.
It is good if you can see these bags in person, put your essentials in them, and try on before purchasing. Regarding the Twist, I think the chain detail on the black version makes the bag a little more dressy. Also, if you like the top handle style, there is the Georges in empreinte leather. I did not try it on and it does have compartments, but if you are in the boutique, you may want to take a look at it as well. Good luck with your decision!