There is actually a big difference. Ostrich, calf, lamb et al are not CITES-covered, endangered species. But many kinds of snakes are.
So by using even captivity-bred, real snakeskin and other exotics, Mulberry is sending out the message that using them cool/glam/in/desirable. And that creates a huge secondary demand market from other brands as well who copycat the top designers' current trends. And those other secondary brands, given their far lower product prices, are definitely not harvesting their self-farmed critters, but most probably buying from poacher supply, and those most definitely don´t care whether their prey is U.N. protected or not.