LaBeouf, 22, was driving when his car was involved in a collision around 3 a.m., according to Los Angeles County Sheriff's Sgt. S. Wolf.
"It was immediately apparent to officers responding on the scene that LaBeouf was intoxicated and he was subsequently placed under arrest,"Wolf said.
Both LeBeouf, who recently co-starred in Indiana Jones and the Kingdom of the Crystal Skull, and his passenger were injured as was the other driver involved in the crash. Wolf said he didn't know the extent of their injuries.
It is not know whether the actor will face felony or misdemeanor charges.