I use to think that I was allergic to the powder in latex gloves because I would develope dry-cracked knuckles.--only my right hand..never my left. But then I realized its WINTER everytime I get this! My knuckles get readyy dry, sometimes itchy too and it makes my knuckles look DARK. I apply cortisone on it but not really too big on lotions & moisturizers on my skin. Does anyone have this too or am I the only one?