I think I am about the 3rd person thats going to say I dont! I was watching Jessica Simpson/Nick Lachey's show a long time ago and Jessica was washing brand new sheets.. it was the first time I heard about anyone doing that and I thought she was crazy! lol. Nevertheless I started washing my new sheets too after that and I find the sheets just dont feel as nice. I like the smell and the feel of brand new, crisp sheets.. and same goes for clothing. After you wash them once its just not the same anymore, they feel used after they've been washed/dried. I do wash towels before use though.