David Duchovny is Hank Moody Famed novelist & NYC transplant Hank relocates to LA after his acclaimed book is optioned, but it later becomes a crappy romantic comedy, which sparks a horrible case of writer's block. He's struggling to get his career back on track with the help of his agent/best friend, raise his pre-teen daughter, all while pining for his ex-girlfriend, who is now engaged to another man. It may sound desperate, but he enjoys life and owns all his various vices - drink, drugs and women - with a refreshing sense of honesty and unapologetic candor. He's holding it together while falling apart, and he doesn't mind it one bit. Evan Handler is Charlie Hank's best friend and agent lives his life on the straight and narrow path and can't understand why Hank can't just kick his various habits and settle down with a good woman. But, underneath, married Charlie envies Hank's swinging lifestyle and Charlie's behavior behind closed doors will contradict his morally sanctified tone and cause problems on the home front.