I am one of those people that lose and gain weight very fast all to my stomach. I lost weight the first week, but my appetite increased. I then started to gain weight because I was eating more. So I have started exercising and the weight does not seem to be coming off so that is my final straw. I do not want to keep putting on the pounds. The drug, I have also read, is interfering with the beta blocker that I take and I am starting to feel that the beta blocker is not working as well either. I am only on 25mg. And I only had a slight problem. I am sure others are worse and need to take the medication, but I have had enough.